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Reimbursement Review

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Title	Brand Name	Generic Name	Files	Therapeutic Area	Recommendation Type	Status	Submission Date	Recommendation Date Sort ascending	Project Number
everolimus	N/A	everolimus	Recommendation and Reasons Responses to the Questions From the Drug Programs Clinical and Pharmacoeconomic Combined Report Stakeholder Feedback on Draft Recommendation Patient, Clinician and Industry Group Input	Tuberous Sclerosis Complex (TSC)	Reimburse with clinical criteria and/or conditions	Complete	Dec 13, 2023	Dec 3, 2024	SX0836-000
enfortumab vedotin	Padcev	enfortumab vedotin	Recommendation and Reasons Patient and Clinician Group Input Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation	Metastatic urothelial cancer	Reimburse with clinical criteria and/or conditions	Complete	May 22, 2024	Nov 29, 2024	PC0353-000
venetoclax	Venclexta	venetoclax	Recommendation and Reasons Patient and Clinician Group input Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation	Chronic lymphocytic leukemia (CLL)	Reimburse with clinical criteria and/or conditions	Complete	May 22, 2024	Nov 28, 2024	PC0362-000
fruquintinib	Fruzaqla	fruquintinib	Recommendation and Reason Patient and Clinician Group input Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation	Metastatic colorectal cancer (mCRC)	Reimburse with clinical criteria and/or conditions	Complete	May 22, 2024	Nov 27, 2024	PC0352-000
lisocabtagene maraleucel	Breyanzi	lisocabtagene maraleucel	Recommendation and Reasons Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation Patient and Clinician Group input	Relapsed or refractory large B-cell lymphoma	Reimburse with clinical criteria and/or conditions	Complete	May 8, 2024	Nov 27, 2024	PG0358-000
Enzalutamide	N/A	Enzalutamide	Recommendation and Reasons Responses to the Questions From the Drug Programs Clinical and Pharmacoeconomic Combined Report Patient, Clinician and Industry Group Input Feedback on Draft Recommendation	Genito-urinary cancer (prostate cancer)	Reimburse with clinical criteria and/or conditions	Complete	Apr 30, 2024	Nov 26, 2024	PX0366-000
Mepolizumab	N/A	Mepolizumab	Recommendation and Reasons Responses to the Questions From the Drug Programs Clinical and Pharmacoeconomic Combined Report Patient and Clinician Group Input Feedback on Draft Recommendation	Eosinophilic Granulomatosis with Polyangiitis	Reimburse with clinical criteria and/or conditions	Complete	Dec 19, 2023	Nov 25, 2024	SX0839-000
ciltacabtagene autoleucel	Carvykti	ciltacabtagene autoleucel	Recommendation and Reasons Clinical, Pharmacoeconomic and Ethics Combined Report Feedback on Draft Recommendation Patient and Clinician Group input	Relapsed or refractory multiple myeloma	Reimburse with clinical criteria and/or conditions	Complete	Apr 18, 2024	Nov 1, 2024	PG0361-000
avapritinib	Ayvakyt	avapritinib	Recommendation and Reasons Patient and Clinician Group input Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation	Advanced Systemic Mastocytosis	Reimburse with clinical criteria and/or conditions	Complete	Apr 19, 2024	Oct 31, 2024	PC0335-000
alectinib	Alecensaro	alectinib	Recommendation and Reason Patient, Clinician and Industry Group Input Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation	ALK-positive NSCLC	Reimburse with clinical criteria and/or conditions	Complete	Apr 18, 2024	Oct 30, 2024	PC0350-000
sotatercept	Winrevair	sotatercept	Recommendation and Reasons Patient and Clinician Group Input Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation	Pulmonary arterial hypertension (WHO group 1)	Reimburse with clinical criteria and/or conditions	Complete	Apr 8, 2024	Oct 21, 2024	SR0828-000
eplontersen	Wainua	eplontersen	Recommendation and Reasons Patient and Clinician Group Input Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation	Polyneuropathy in hereditary transthyretin-mediated amyloidosis	Reimburse with clinical criteria and/or conditions	Complete	Apr 9, 2024	Oct 21, 2024	SR0826-000
clindamycin plus benzoyl perox...	Cabtreo	clindamycin plus benzoyl peroxide and adapalene	Recommendation and Reason Patient and Clinician Group input Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation	acne vulgaris	Reimburse with clinical criteria and/or conditions	Complete	Mar 8, 2024	Oct 18, 2024	SR0794-000
danicopan	Voydeya	danicopan	Recommendation and Reasons Patient and Clinician Group Input Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation	Paroxysmal nocturnal hemoglobinuria (PNH)	Reimburse with clinical criteria and/or conditions	Complete	Apr 4, 2024	Oct 18, 2024	SR0815-000
elexacaftor/tezacaftor/ivacaft...	Trikafta	elexacaftor/tezacaftor/ivacaftor and ivacaftor	Recommendation and Reason Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation Patient and Clinician Group input	Cystic fibrosis, F508del or responsive CFTR mutation, 2 years and older	Reimburse with clinical criteria and/or conditions	Complete	Mar 5, 2024	Oct 17, 2024	SR0837-000
burosumab	Crysvita	burosumab	Recommendation and Reason Patient and Clinician Group input Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation	Treatment of X-Linked Hypophosphatemia	Reimburse with clinical criteria and/or conditions	Complete	Jan 2, 2024	Oct 10, 2024	SR0818-000
lebrikizumab	Ebglyss	lebrikizumab	Recommendation and Reason Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation Patient and Clinician Group input	atopic dermatitis	Do not reimburse	Complete	Nov 1, 2023	Oct 9, 2024	SR0819-000
ivosidenib	Tibsovo	ivosidenib	Recommendation and Reason Patient and Clinician Group Input Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation	Acute myeloid leukemia (AML)	Reimburse with clinical criteria and/or conditions	Complete	Mar 19, 2024	Oct 4, 2024	PC0349-000
pembrolizumab	Keytruda	pembrolizumab	Recommendation and Reason Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation Patient and Clinician Group Input	Gastric or gastroesophageal junction (GEJ) adenocarcinoma	Reimburse with clinical criteria and/or conditions	Complete	Mar 13, 2024	Oct 4, 2024	PC0356-000
abemaciclib	Verzenio	abemaciclib	Recommendation and Reason Patient and Clinician Group input Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation	Adjuvant treatment of HR-positive, HER2-negative early breast cancer	Reimburse with clinical criteria and/or conditions	Complete	Feb 9, 2024	Oct 3, 2024	PC0345-000
osimertinib	Tagrisso	osimertinib	Recommendation and Reason Patient and Clinician Group Input Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation	Non-small cell lung cancer	Reimburse with clinical criteria and/or conditions	Complete	Dec 11, 2023	Oct 3, 2024	PC0336-000
baricitinib	Olumiant	baricitinib	Recommendation and Reasons Patient and Clinician Group input Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation	Alopecia areata, severe	Reimburse with clinical criteria and/or conditions	Complete	Mar 4, 2024	Sep 13, 2024	SR0843-000
secukinumab	Cosentyx	secukinumab	Recommendation and Reasons Patient and Clinician Group input Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation	Hidradenitis suppurativa	Reimburse with clinical criteria and/or conditions	Complete	May 10, 2023	Sep 12, 2024	SR0781-000
capivasertib	Truqap	capivasertib	Recommendation and Reasons Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation Patient and Clinician Group Input	HR-positive, HER2-negative locally advanced or metastatic breast cancer	Reimburse with clinical criteria and/or conditions	Complete	Feb 14, 2024	Aug 30, 2024	PC0341-000
Brentuximab vedotin	Adcetris	Brentuximab vedotin	Recommendation and Reasons Clinical and Pharmacoeconomic Combined Report Feedback on Draft Recommendation Patient and Clinician Group Input	Hodgkin lymphoma	Reimburse with clinical criteria and/or conditions	Complete	Apr 18, 2024	Aug 29, 2024	PC0371-000

Health Technology Review

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Title	Files	Last Updated Sort ascending	Project Sub Line	Status	Project Number
Health System Readiness for Disease-Modifying Therapies for Alzheimer's Disease	Final Report Summary Report	Jan 30, 2025		Active	CM0003-000
Utilization of Drugs in Patients With Major Neurocognitive Disorder		Jan 29, 2025	Technology Review	In Progress	HC0099-000
Trends in hydromorphone prescribing in Canada from 2018 to 2024		Jan 29, 2025	Technology Review	In Progress	HC0096-000
Virtual Mental Health Counselling	Virtual Mental Health Counselling	Jan 20, 2025	Rapid Review	Completed	RC1569-000
Methadone for Surgical Patients	Methadone for Surgical Patients	Jan 9, 2025	Rapid Review	Completed	RC1565-000
Antiviral Drugs for the Treatment of Suspected or Confirmed Influenza A or Influenza B		Dec 16, 2024	Systematic Review	In Progress	RE0052-000
Icatibant Implementation Advice Panel	Implementation Advice for Icatibant	Dec 16, 2024	Technology Review	Completed	HC0097-000 - SX0849-000
Use of Oral Fluoroquinolones in Canada: Drug Utilization Study Update	Report Protocol Summary Report	Dec 6, 2024	Technology Review	Complete	HC0073-000
Artificial Intelligence–Assisted Colonoscopy for Detecting Polyps, Adenomas, Precancerous Lesions, and Colorectal Cancer	Artificial Intelligence–Assisted Colonoscopy for Detecting Polyps, Adenomas, Pr…	Dec 5, 2024	Rapid Review	Completed	RC1559-000
RapidAI for Stroke Detection	Final Recommendation RapidAI for Stroke Detection: Main Report Supporting Information for RapidAI Review Supporting Information for AI Implementation Review	Dec 5, 2024	Optimal Use	Active	OP0556-000
Attention-Deficit/Hyperactivity Disorder Medications for Adults	Attention-Deficit/Hyperactivity Disorder Medications for Adults	Dec 3, 2024	Rapid Review	Completed	RC1556-000
Overview of Systematic Reviews of Immune Checkpoint Inhibitors in Non–Small-Cell Lung Cancer with EGFR, ALK, ROS1, and RET Actionable Driver Mutations	Summary Report Final Report Protocol - Final	Nov 26, 2024	Systematic Review	Completed	RE0050-000
Utilization of Cancer Therapies for Advanced Non–Small Cell Lung Cancer With an Oncogenic Driver Mutation	Summary Report Utilization of Cancer Therapies for Advanced Non–Small Cell Lung Cancer With an…Final Project Protocol	Nov 26, 2024	Technology Review	Completed	HC0084-OS0008
Benchmarking CT and MRI exams		Nov 21, 2024		In Progress	CM0016-000
Optimal Wait Times		Nov 21, 2024		In Progress	CM0014-000
Long-Acting Inhaled Drugs for Chronic Obstructive Pulmonary Disease		Nov 15, 2024	Therapeutic Review	Active	TR0016-000
Federal, Provincial, and Territorial Coverage of Diagnostic Sleep Studies		Nov 13, 2024	Environmental Scan	Completed	ES0382-000
Midazolam Compared With Lorazepam in Adults to Control Seizures	Midazolam Compared With Lorazepam in Adults to Control Seizures	Nov 6, 2024	Rapid Review	Completed	RC1554-000
Utilization of Long-Acting Injectable Antipsychotics		Nov 1, 2024	Technology Review	In Progress	HC0098-000
Review of Guidelines on Bupropion for Depression	Review of Guidelines on Bupropion for Depression	Oct 30, 2024	Rapid Review	Completed	RC1558-000
GLP-1 Receptor Agonists and Self-Harm		Oct 29, 2024	Observational Study	Active	OS0009-000
Gabapentin for Seizures	Gabapentin for Seizures	Oct 25, 2024	Rapid Review	Completed	RC1557-000
Early Biologic Treatment for Inflammatory Bowel Disease	Early Biologic Treatment for Inflammatory Bowel Disease	Oct 25, 2024	Rapid Review	Completed	RC1552-000
The Utilization of PCSK9 Inhibitors in Familial Hypercholesterolemia		Oct 22, 2024	Technology Review	Active	HC0094-000
Airway Management in Out-of-Hospital Emergencies	Airway Management in Out-of-Hospital Emergencies	Oct 21, 2024	Rapid Review	Completed	RC1555-000

Horizon Scan

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Displaying 26 - 50 of 110

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Title	Files	Last Updated Sort ascending	Project Sub Line	Status	Project Number
Facial Analysis Technology for Pain Detection	Facial Analysis Technology for Pain Detection	Jul 31, 2023	Health Technology Update	Completed	EN0047-000
An Overview of Clinical Applications of Virtual and Augmented Reality	An Overview of Clinical Applications of Virtual and Augmented Reality	Jul 31, 2023	Emerging Health Technologies	Completed	EH0111-000
Xylazine Test Strips for Drug Checking	Xylazine Test Strips for Drug Checking	Jul 17, 2023	Health Technology Update	Completed	EN0049-000
Hearing Aids and Dementia	Hearing Aids and Dementia	Jul 6, 2023	Emerging Health Technologies	Completed	EH0120-000
Rapid HIV Self-Testing	Rapid HIV Self-Testing	Jun 30, 2023	Emerging Health Technologies	Completed	EH0118-000
Hybrid Operating Rooms Suites	Hybrid Operating Rooms Suites	Jun 9, 2023	Emerging Health Technologies	Completed	EH0121-000
An Overview of Pharmacogenomic Testing for Psychiatric Disorders	An Overview of Pharmacogenomic Testing for Psychiatric Disorders	Jun 6, 2023	Emerging Health Technologies	Completed	EH0115-000
Cognitive Health Assessment Management Platform	Cognitive Health Assessment Management Platform	May 10, 2023	Health Technology Update	Completed	EN0046-000
Reducing the Environmental Impact of Clinical Care	Reducing the Environmental Impact of Clinical Care	Apr 20, 2023		Completed	EH0112-000
Laser Treatment for Lower Back Pain	Laser Treatment for Lower Back Pain	Apr 12, 2023	Health Technology Update	Completed	EN0044-000
Point-of-Care Tests for Pancreatitis	Point-of-Care Tests for Pancreatitis	Mar 6, 2023	Health Technology Update	Completed	EN0045-000
Wastewater Surveillance for Communicable Disease	Wastewater Surveillance for Communicable Disease	Feb 21, 2023	Emerging Health Technologies	Completed	EH0114-000
Robotic Surgical Systems for Orthopedics	Robotic Surgical Systems for Orthopedics	Nov 3, 2022	Emerging Health Technologies	Completed	EH0108-000
Rapid Syphilis Testing	Rapid Syphilis Testing	Nov 2, 2022	Health Technology Update	Completed	EN0043-000
Vagus Nerve Stimulation for the Treatment of Post–COVID-19 Condition	Vagus Nerve Stimulation for the Treatment of Post–COVID-19 Condition	Sep 20, 2022	Health Technology Update	Active	EN0040-000
An Overview of Comprehensive Genomic Profiling Technologies to Inform Cancer Care	An Overview of Comprehensive Genomic Profiling Technologies to Inform Cancer Ca…	Aug 10, 2022	Emerging Health Technologies	Completed	EH0106-000
Understanding the Portrait of Dementia Care in Canada: Our Panel of Experts	Understanding the Portrait of Dementia Care in Canada: Our Panel of Experts	Aug 10, 2022	Emerging Health Technologies	Completed	EH0110-000
Autologous Hematopoietic Stem Cell Transplant for People With Multiple Sclerosis	HTERP Guidance Statement – AHSCT for treatment of Multiple Sclerosis Horizon Scan - Bulletin	Jul 20, 2022	Optimal Use	Complete	EH0093 / OP0551
Trace Amine-Associated Receptor 1 Agonists for Schizophrenia	Trace Amine-Associated Receptor 1 Agonists for Schizophrenia	Jul 15, 2022	Emerging Health Technologies	Completed	EH0105-000
Self-Collection of Nose and Throat Swab Samples for SARS-CoV-2 Antigen Testing	Self-Collection of Nose and Throat Swab Samples for SARS-CoV-2 Antigen Testing	Jun 13, 2022	Emerging Health Technologies	Completed	EH0109-000
An Overview of Continuous Learning Artificial Intelligence-Enabled Medical Devices	An Overview of Continuous Learning Artificial Intelligence-Enabled Medical Devi…	May 24, 2022	Emerging Health Technologies	Completed	EH0102-000
An Overview of New and Emerging Technologies for Early Diagnosis of Alzheimer Disease	An Overview of New and Emerging Technologies for Early Diagnosis of Alzheimer D…	May 16, 2022	Emerging Health Technologies	Completed	EH0103-000
Tirzepatide for Type 2 diabetes mellitus	Tirzepatide for Type 2 diabetes mellitus	Apr 26, 2022	Emerging Health Technologies	Completed	EH0104-000
Emerging Multi-Cancer Early Detection Technologies	Emerging Multi-Cancer Early Detection Technologies	Apr 22, 2022	Health Technology Update	Completed	EN0037-000
Electrospun Healing Fibres for the Management of Burns and Wounds	Electrospun Healing Fibres for the Management of Burns and Wounds	Mar 23, 2022	Health Technology Update	Completed	EN0033-000

Projects in Progress

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Title	Description	Files	Last Updated Sort ascending	Project Line	Project Sub Line	Project Number
Formulary Management of Targeted Immune Modulators for Ulcerative Colitis			Jun 24, 2022	Health Technology Review	Technology Review	HD0010-000
Criteria for conducting Environmental Assessments in CADTH HTAs			Jun 5, 2019	Health Technology Review		MG0017-000

View All Reports

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Title	Files	Last Updated Sort ascending	Project Line	Project Sub Line	Status	Project Number
dupilumab	Patient and Clinician Group Input	Apr 14, 2025	Reimbursement Review		Active	SR0876-000
dupilumab	Patient and Clinician Group input	Apr 14, 2025	Reimbursement Review		Active	SR0878-000
cipaglucosidase alfa and miglustat	Patient and Clinician Group input	Apr 14, 2025	Reimbursement Review		Active	SR0871-000
guselkumab	Patient and Clinician Group input	Apr 14, 2025	Reimbursement Review		Active	SR0874-000
elafibranor	Patient and Clinician Group input	Apr 14, 2025	Reimbursement Review		Active	SR0865-000
nemolizumab	Patient and Clinician Group Input	Apr 14, 2025	Reimbursement Review		Active	SR0869-000
bimekizumab	Patient and Clinician Group input	Apr 14, 2025	Reimbursement Review		Active	SR0856-000
ravulizumab	Recommendation and Reason Patient and Clinician Group input	Apr 14, 2025	Reimbursement Review		Active	SR0855-000
ferric carboxymaltose	Draft Recommendation and Reasons Patient and Clinician Group input	Apr 14, 2025	Reimbursement Review		Active	SR0852-000
iptacopan	Recommendation and Reason Patient and Clinician Group input	Apr 14, 2025	Reimbursement Review		Active	SR0851-000
semaglutide	Patient and Clinician Group input	Apr 14, 2025	Reimbursement Review		Active	SR0841-000
talazoparib	Patient and Clinician Group Input	Apr 14, 2025	Reimbursement Review		Active	PC0417-000
abemaciclib	Patient and Clinician Group input	Apr 14, 2025	Reimbursement Review		Active	PC0409-000
pembrolizumab		Apr 14, 2025	Reimbursement Review		Active	PC0411-000
venetoclax	Patient and Clinician Group Input	Apr 14, 2025	Reimbursement Review		Active	PC0402-00
osimertinib	Patient and Clinician Group input	Apr 14, 2025	Reimbursement Review		Active	PC0398-000
abemaciclib	Patient and Clinician Group input	Apr 14, 2025	Reimbursement Review		Active	PC0400-000
nivolumab and ipilimumab		Apr 14, 2025	Reimbursement Review		Active	PC0396-000
durvalumab	Patient and Clinician Group input	Apr 14, 2025	Reimbursement Review		Active	PC0389-000
pembrolizumab	Patient and Clinician Group Input	Apr 14, 2025	Reimbursement Review		Active	PC0383-000
belantamab mafodotin, pomalidomide, dexamethasone	Patient and Clinician Group Input	Apr 14, 2025	Reimbursement Review		Active	PC0380-000
inavolisib	Patient and Clinician Group Input	Apr 14, 2025	Reimbursement Review		Active	PC0382-000
quizartinib	Patient and Clinician Group Input	Apr 14, 2025	Reimbursement Review		Active	PC0359-000
talquetamab	Recommendation and Reasons Patient and Clinician Group Input	Apr 14, 2025	Reimbursement Review		Active	PC0363-000
Evidence Review for Brineura (cerliponase alfa)	Proposed Scope	Apr 11, 2025	Health Technology Review	Technology Review	Active	HC0106-000