Evidence on Pain Management
You’ll find our best evidence on the management of pain. We’ll be updating this Evidence Bundle regularly with more evidence, including rapid evidence reviews (Rapid Response Reports), Environmental Scans, Horizon Scans, and our larger Optimal Use projects with expert recommendations, as they are completed.
We’ve selected the following materials to get you started:
- Ketamine for Chronic Non-Cancer Pain: A 2023 Update (Health Technology Review, January 9, 2024)
- Facial Analysis Technology for Pain Detection (Horizon Scan, July 31, 2023)
- Internet-Delivered Cognitive Behavioural Therapy for the Management of Chronic NonCancer Pain: A Summary of a Health Technology Assessment (Tool, November 9, 2022)
- Models of Care for Chronic Non-Cancer Pain: A Summary of the Research on Stepped Care and Hub-and-Spoke Models (Tool, October 14, 2022)
- Internet-Delivered Cognitive Behavioural Therapy in the Treatment of Chronic Non-Cancer Pain (Health Technology Assessment, October 3, 2022
- Pre-Surgical Screening Tools and Risk Factors for Chronic Post-Surgical Pain: A Summary (Tool, May 30, 2022)
In this Bundle
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Gabapentin for Adults With Neuropathic Pain: A Review
A summary of five of our reports, published between 2014 and 2018, on gabapentin for neuropathic pain.
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Medications Containing Low-dose Codeine for the Treatment of Pain and Coughs
(Rapid Review, August 20, 2021)
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Codeine for Pain Related to Caesarean Section: A Review of Clinical Effectiveness
(Summary with Critical Appraisal, March 3, 2021)
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Codeine for Acute Dental Pain and Acute Pain Related to Dental Procedures
(Summary with Critical Appraisal, March 3, 2021)
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Capsaicin for Acute or Chronic Non-Cancer Pain: A Review of Clinical Effectiveness, Safety, and Cost-Effectiveness
(Summary with Critical Appraisal, July 13, 2020)
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Capsaicin for Acute or Chronic Non-Cancer Pain: A Review of Guidelines
(Summary with Critical Appraisal, June 29, 2020)
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External Supports for the Treatment of Ankle Sprain: A Review of Clinical Effectiveness
(Summary with Critical Appraisal, May 7, 2020)
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Psychotherapy for the Treatment of Acute Musculoskeletal Pain: A Review of Clinical Effectiveness and Guidelines
(Summary with Critical Appraisal, April 27, 2020)
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Exercise for the Treatment of Ankle Sprain: A Review of Clinical Effectiveness and Guidelines
(Summary with Critical Appraisal, April 13, 2020)
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Stepped Care Models for Chronic Pain
(Technology Review, May 30, 2022)
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Hub-and-Spoke Models of Care for Chronic Pain
(Technology Review, May 2, 2022)
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Models of Care for Chronic Pain: An Environmental Scan
(Environmental Scan, April 12, 2021)
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Gabapentin for Adults With Neuropathic Pain: A Review
A summary of five of our reports, published between 2014 and 2018, on gabapentin for neuropathic pain.
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Ketamine for Chronic Non-Cancer Pain: A 2023 Update
(Summary with Critical Appraisal, January 9, 2024)
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Intrathecal Drug Delivery Systems for Cancer Pain
(Technology Review, November 6, 2023)
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IV Acetaminophen for Acute Pain in Emergency Departments
(Rapid Review, October 6, 2023)
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Platelet-Rich Plasma Injections for Lower Back Pain
(Rapid Review, July 31, 2023)
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Codeine for Pain Related to Osteoarthritis of the Knee and Hip: A Review of Clinical Effectiveness
(Summary with Critical Appraisal, December 14, 2020)
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Capsaicin for Acute or Chronic Non-Cancer Pain: A Review of Clinical Effectiveness, Safety, and Cost-Effectiveness
(Summary with Critical Appraisal, July 13, 2020)
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Capsaicin for Acute or Chronic Non-Cancer Pain: A Review of Guidelines
(Summary with Critical Appraisal, June 29, 2020)
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Ketamine for Chronic Non-Cancer Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines
(Summary with Critical Appraisal, June 2, 2020)
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Pharmacological Interventions for Chronic Pain in Pediatric Patients: A Review of Guidelines
(Summary with Critical Appraisal, May 5, 2020)
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Therapeutic Mattresses for Chronic Pain
(Rapid Review, April 6, 2022)
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Custom-Made Foot Orthotics for People with Lower Limb Conditions
(Rapid Review, February 18, 2022)
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Orthopedic Footwear for People With Lower-Limb Conditions
(Rapid Review, January 24, 2022)
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Customized or Prefabricated Shoe Inserts for Chronic, Non-Cancer Pain: A Review of Clinical Effectiveness
(Summary with Critical Appraisal, April 20, 2020)
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Body Weight Modification Interventions for Chronic Non-Cancer Pain: A Review of Clinical Effectiveness
(Summary with Critical Appraisal, March 31, 2020)
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Orthotic Bracing or Splinting of Upper Extremities in Patients with Chronic, Non-Cancer Pain: A Review of Clinical Effectiveness
(Summary with Critical Appraisal, March 2, 2020)
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Manual Therapy for Persistent, Non-Cancer Back and Neck Pain: A Review of Clinical Effectiveness
(Summary with Critical Appraisal, March 2, 2020)
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Physical Activity for Chronic Osteoarthritic Knee Pain: A Review of Clinical Effectiveness
(Summary with Critical Appraisal, February 17, 2020)
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Internet-Delivered Cognitive Behavioural Therapy in the Treatment of Chronic Non-Cancer Pain
(Optimal Use, October 3, 2022)
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Radiofrequency Ablation for Chronic Knee, Hip, and Shoulder Pain
(Rapid Review, October 11, 2023)
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Facial Analysis Technology for Pain Detection
(Health Technology Update, July 31, 2023)
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Laser Treatment for Lower Back Pain
(Health Technology Update, April 12, 2023)
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Pre-Surgical Screening Tools and Risk Factors for Chronic Post-Surgical Pain
(Technology Review, May 17, 2022)
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Screening Tools for Chronic Postsurgical Pain: A Review of Clinical Utility
(Summary with Critical Appraisal, January 15, 2021)
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Internet-Delivered Cognitive Behavioural Therapy for the Management of Chronic NonCancer Pain: A Summary of a Health Technology Assessment
(Tools, October 19, 2022)
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Models of Care for Chronic Non-Cancer Pain: A Summary of the Research on Stepped Care and Hub-and-Spoke Models
(Tools, October 14, 2022)
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Pre-Surgical Screening Tools and Risk Factors for Chronic Post-Surgical Pain: A Summary
(Tools, May 30, 2022)
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Assessing and Managing Chronic Non-Cancer Pain
(Tools, November 30, 2021)
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Infographic: Models of Care for Chronic Pain
(Tools, August 30, 2021)
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Codeine for Pain: A Synopsis of the Evidence
A summary of the evidence (based on a number of our reviews) on codeine for pain.
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In Brief: Models of Care for Chronic Pain
( ES0350-000, June 23, 2021)
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Non-Opioid Options for Managing Pain
To help support decisions about managing pain, we have been reviewing the evidence on different treatment options for various types of pain. Here, you’ll find the highlights of many of these evidence reviews.
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Acute Pain Management: Non-Pharmacological Interventions
Over the last few years, we have been asked to review, the clinical effectiveness evidence and the recommendations from evidence-based guidelines for treating various acute pain conditions with non-pharmacological interventions. Here, you’ll find the evidence highlights related to those evidence reviews.
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Non-Drug Ways to Manage Chronic Pain
Resources for people living with chronic pain and resources for clinicians.
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Physical Activity for Chronic Pain: A Synopsis of the Evidence
(Tools, July 28, 2020)
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In Brief: Acupuncture for Chronic Non-Cancer Pain: A Review
(Tools, February 5, 2020)
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Non-Pharmacological Interventions for Chronic Non-Cancer Pain: Acupuncture
(Webinar, March 30, 2020)
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Non-Pharmacological Interventions for Chronic Non-Cancer Pain: Physical Activity
(Webinar, September 23, 2020)
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Non-Pharmacological Interventions for Chronic Non-Cancer Pain: The Science of Mindfulness
(Webinar, November 1, 2019)
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Pain Management & Gabapentinoids
(Webinar, March 12, 2019)