Last Updated : July 31, 2023
Details
FilesProject Status:
Completed
Project Line:
Health Technology Review
Project Sub Line:
Rapid Review
Project Number:
RC1485-000
Question
- What is the clinical effectiveness of platelet-rich plasma injections for the treatment of lower back pain in adults?
Key Message
Platelet-rich plasma injections (PRPIs) might be better than other injections (including steroid injections) for patients with lower back pain in reducing pain and enhancing patient satisfaction, without increasing the risk of major complications or serious adverse events. For patients with low back pain who received PRPI, disability measures were lower up to 6 months after treatment than before PRPI, while MRI findings were unchanged from baseline. The included systematic reviews did not report any major complications or serious adverse events related to PRPIs. We did not find any studies reporting on the comparisons between PRPI and other conservative treatments such as non-steroidal anti-inflammatory drugs, exercise, or physiotherapy that met the inclusion criteria for this report.
Files
Last Updated : July 31, 2023