Canada’s Drug Agency | Drugs, Health Technologies and Systems.
Canada’s Drug Agency | Drugs, Health Technologies and Systems.

Somatropin for Turner Syndrome

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Project Status:
Completed
Project Line:
Health Technology Review
Project Sub Line:
Rapid Review
Project Number:
RC1493-000
Expected finish date:

Question

  1. What are the evidence-based guidelines regarding the use of growth hormone therapy for children with Turner syndrome?

Key Message

Early initiation of growth hormone therapy is recommended in children with Turner syndrome if the child already has growth failure or has a high chance of short stature (1 guideline). Growth hormone treatment can be started at 45 mcg/kg/day to 50 mcg/kg/day (1 guideline). Monitor treatment by regular height measurements and assessment of levels of insulin-like growth factor-I (1 guideline). Continue treatment until the desired height is achieved or when no more growth potential remains (1 guideline).

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Somatropin for Turner Syndrome View PDF
Last Updated : August 4, 2023