Reimbursement Review Reports

Our Reimbursement Reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class. The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec. Implementation advice and funding algorithms are provided where applicable.

For each drug, plasma product, or cell and gene therapy reviewed in the Drug Reimbursement Review process, there is an opportunity for patient groups and clinician groups to provide input and feedback. See Reimbursement Review Open Calls for Input and Feedback.

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Brand Name Sort descending Generic Name Therapeutic Area Recommendation Type Project Status Date Submission Received Date Recommendation Issued
Xgeva Denosumab (Drug Plan Submission) Prevention of skeletal-related events due to bone metastases from other solid tumors (excluding breast and prostate cancer), including non-small cell lung cancer List with clinical criteria and/or conditions Complete
Xiaflex Collagenase clostridium histolyticum Dupuytren’s contracture List with criteria/condition Complete
XigDuo dapagliflozin/metformin hydrochloride Diabetes Mellitus, Type 2 Reimburse with clinical criteria and/or conditions Complete
Xofluza baloxavir marboxil Influenza Canada’s Drug Agency is unable to make a reimbursement recommendation as the manufacturer has not filed a submission. Not filed
Xolair omalizumab Chronic rhinosinusitis with nasal polyps Canada’s Drug Agency is unable to make a reimbursement recommendation as the manufacturer has not filed a submission. Not filed
Xolair Omalizumab Chronic idiopathic urticaria List with clinical criteria and/or conditions Complete
Xolair Omalizumab Asthma, severe persistent Cancelled
Xolair Omalizumab Asthma, severe persistent Do not list Complete
Xolair Omalizumab (Drug Plan Submission) Asthma, severe persistent Reimburse with clinical criteria and/or conditions Complete
Xospata Gilteritinib Reimburse with clinical criteria and/or conditions Complete
Xpovio selinexor Multiple myeloma Reimburse with clinical criteria and/or conditions Complete
Xtandi Enzalutamide mHSPC Reimburse with clinical criteria and/or conditions Complete
Xtandi Enzalutamide Non-metastatic castration-resistant prostate cancer (nm-CRPC) Reimburse with clinical criteria and/or conditions Complete
Xtandi Enzalutamide First Line Metastatic Castration-Resistant Prostate Cancer Reimburse with clinical criteria and/or conditions Complete
Xtandi Enzalutamide Metastatic Castration Resistant Prostate Cancer Reimburse with clinical criteria and/or conditions Complete
Xultophy insulin degludec + liraglutide Diabetes mellitus, Type 2 Reimburse with clinical criteria and/or conditions Complete
Xydalba dalbavancin Acute bacterial skin and skin structure infections Reimburse with clinical criteria and/or conditions Complete
Xyrem Sodium oxybate Narcolepsy Withdrawn
Xyrem Sodium oxybate Narcolepsy Do not list Complete
Yasmin Drospirenone /ethinyl estradiol Contraceptive, oral List Complete
Yervoy Ipilimumab Advanced Melanoma Reimburse with clinical criteria and/or conditions Complete
Yervoy Ipilimumab First Line Advanced Melanoma Reimburse with clinical criteria and/or conditions Complete
Yescarta axicabtagene ciloleucel Diffuse large B-cell lymphoma (DLBCL) or high-grade B-cell lymphoma (HGBL) Reimburse with clinical criteria and/or conditions Complete
Yescarta axicabtagene ciloleucel Relapsed or refractory follicular lymphoma Reimburse with clinical criteria and/or conditions Complete
Yondelis Trabectedin Metastatic Liposarcoma or Leiomyosarcoma Do not reimburse Complete