Last Updated : July 28, 2021
Details
FilesProject Status:
Completed
Project Line:
Health Technology Review
Project Sub Line:
Rapid Review
Project Number:
RC1372-000
Question
- What is the clinical utility of point-of-care devices that measure acetaminophen toxicity for patients with suspected overdose?
- What is the cost-effectiveness of point-of-care devices that measure acetaminophen toxicity for patients with suspected overdose?
- What are the evidence-based guidelines regarding the administration of IV N-acetylcysteine for patients with acute acetaminophen overdose?
Key Message
Evidence on the clinical utility and cost-effectiveness of point-of-care devices could not be identified.
Two evidence-based guidelines recommend a 2-bag regimen of N-acetylcysteine, consisting of both a loading dose and maintenance dose, administered by IV for patients with acute acetaminophen overdose.
Files
Last Updated : July 28, 2021